接种COVID-19疫苗后的皮肤Rosai-Dorfman疾病:罕见发生,具有具有挑战性的呈现
Zainab Harb1, Zainab Toorani1, Mahmood Ali1
1Department of Pathology, Salmaniya Medical Complex, Manama, Bahrain.
Seminars in musculoskeletal radiology
|October 7, 2025
概括
一种罕见的皮肤疾病,罗莎伊-多夫曼病,在一个COVID-19疫苗接种地点发生在一个年轻女孩身上. 这一案例凸显了接种疫苗后皮肤Rosai-Dorfman病的诊断挑战.
科学领域:
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
- 免疫学 免疫学 免疫学
背景情况:
- 罗莎-多尔夫曼病是一种罕见的细胞瘤,通常会影响淋巴结.
- 可能会发生外节干扰,包括皮肤和皮下组织.
- 皮肤Rosai-Dorfman病不常见,可以模仿其他疾病.
研究的目的:
- 报告一种独特的皮肤Rosai-Dorfman疾病病例.
- 描述其在COVID-19疫苗接种地点发生的情况.
- 为了强调诊断挑战.
主要方法:
- 一个13岁女孩的病例介绍,在接种疫苗后,她的手臂胀了一年.
- 临床检查,成像 (超声波,MRI) 和超声波导向活检.
- 用免疫组织化学 (S100,CD68,OCT-2) 对切除的质量的组织病理学检查.
主要成果:
- 切割揭示了多的皮下脂肪透物.
- 组织病理学显示大基质细胞与emperipolesis,阳性S100,CD68和OCT-2.
- 诊断证实为罗莎伊-多夫曼病.
结论:
- 皮肤Rosai-Dorfman病可以表现为COVID-19疫苗接种的罕见并发症.
- 这次演讲给临床医生,放射科医生和病理学家带来了诊断挑战.
- 早期识别和活检对于准确的诊断和管理至关重要.
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