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在瘤发生过程中,HRS通过定不稳定的蛋白质来维持线粒体平衡

Bo-Lin Xiao1, Jin-Bang Li1, Zhuo-Kun Chen1

  • 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei, 430079, China.

International journal of biological macromolecules
|October 7, 2025
PubMed
概括

在黑色素瘤中,肝细胞生长因子调节的氨酸激酶基质 (HRS) 缺失通过损害线粒体功能和代谢适应来延缓瘤生长. 恢复线粒体蛋白质稳定可以挽救这些缺陷,这表明HRS是潜在的治疗点.

关键词:
在HRS中,HRS是HRS.线粒体中的线粒体.瘤发生的起源

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