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肥胖和体重变化在八年期间与喘发病率的关系

Reshed Abohalaka¹, Selin Ercan², Pinja Ilmarinen^3,4

¹Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, Medicinaregatan 1F, Box 424, 405 30, Gothenburg, Sweden. reshed.abohalaka@gu.se.

Scientific reports

|October 7, 2025

概括

肥胖和体重增加增加了喘风险,特别是在中年妇女中. 控制体重对于喘预防和护理策略至关重要.

科学领域:

流行病学流行病学
公共卫生公共卫生
呼吸系统医学呼吸系统医学

背景情况:

横截面研究表明,肥胖和喘患病率增加之间存在联系.
需要纵向数据来澄清体重变化与喘发病率之间的关系.

研究的目的:

为了研究肥胖,体重变化和8年喘发病率之间的关联,在一个基于人口的成年队列中.
为了确定新发喘的特定体重相关风险因素.

主要方法:

一项以人口为基础的队列研究 (西瑞典喘研究),2008年有18087名参与者,8年后有12449名参与者.
参与者填写了评估身体质量指数 (BMI) 和医生诊断的喘的问卷.
喘发病率计算为每1000人/年,肥胖被定义为BMI≥30 kg/m2,超重被定义为25 ≤BMI<30 kg/m2.

主要成果:

在基线没有喘的参与者中,喘发病率为每1000人年1.8.
在中年成人 (40-60岁) 观察到更高的喘发病率,这些人获得了≥4个BMI单位或肥胖且体重稳定.
随着体重增加 (≥0.5 BMI单位),喘风险的剂量依赖性显著增加.
在基线时的肥胖,无论体重变化,与稳定的正常体重相比,与更高的喘风险有关.
体重增加和肥胖症对喘发病的风险显著增加,特别是在女性中.

结论:

体重管理对于预防和护理喘至关重要.
医疗保健提供者应该整合体重管理策略,特别是对于超重或肥胖的中年女性.
了解体重变化对喘发病率的影响,可以为公共卫生干预提供信息.

关键词:

喘喘是一种这就是为什么BMI是BMI.肥胖问题肥胖问题风险风险风险风险风险在WSAS中,使用的是WSAS.体重变化体重变化

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