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Updated: Jan 15, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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Published on: April 12, 2019

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揭示细胞外矩阵在骨髓瘤瘤微环境中的作用,通过综合转录学和实验验证实验验验证

Yuyang Liu1,2,3, Yuchen Han1,4, Zixuan Guo1,4

  • 1Senior Department of Orthopedics, Chinese PLA General Hospital, Beijing, China.

Cancer gene therapy
|October 7, 2025
PubMed
概括

原体V型α2 (COL5A2) 通过激活焦点粘附信号和细胞交叉声调来驱动骨髓瘤 (OS) 细胞的增殖. 向COL5A2和特定的细胞群可以改善OS的预后和治疗策略.

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