18F-FDG PET/CT参数和标准摄入值预测肺癌中逆侧肺转移的肺癌转移
Büşra Özdemir Günay1, Funda Üstün2
1Giresun Training and Research Hospital, Clinic of Nuclear Medicine, Giresun, Türkiye.
Molecular imaging and radionuclide therapy
|October 8, 2025
概括
肺癌中的逆侧肺膜转移 (CLM) 是由ipsilateral结节,多叶流液和多叶转移预测的. 18F-FDG PET/CT成像有助于识别这些CLM的预测因素.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 逆侧肺膜转移 (CLM) 是肺癌的一个不常见但显著的模式.
- 驱动CLM及其预测因素的精确机制仍然不完全理解.
- F-氧葡萄糖正子发射断层扫描/计算机断层扫描 (F-FDG PET/CT) 是肺癌分期的关键成像方式.
研究的目的:
- 评估F-FDG PET/CT在肺癌患者中识别CLM的附加值.
- 调查与CLM发展相关的原因和预测因素.
- 为了将成像发现与组织病理学数据和生存结果相关联.
主要方法:
- 根据第九种瘤结节转移 (TNM) 分类的肺癌患者的回顾性分析.
- 对患有和没有CLM的患者进行比较,包括患有远程转移到其他器官的患者.
- 详细记录F-FDG PET/CT发现:原发性瘤特征,多发性状况,额外转移的存在,以及标准化吸收值 (SUV).
主要成果:
- 在125例中观察到CLM,其中81例在诊断时和44例在随访期间.
- 与对照组相比,CLM组显示出卫星结节,其他侧侧叶结节,多发性转移和多发性溢液的显着较高率.
- 主要瘤中没有缩,并存在ipsilateral结节/pleural参与是CLM的显著预测因素.
结论:
- F-FDG PET/CT在确定肺癌中CLM的预测因素方面发挥着至关重要的作用.
- 侧结节,多叶膜溢出和多叶膜转移是预测CLM的重要指标.
- 这些成像发现可以帮助风险分层和肺癌患者的管理.
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