对双相情感障碍中抑郁,躁狂和焦虑症状的运动干预:系统性审查和元分析
Xinmo Li1, Feike Liu1, Feng Ding2
1Capital University of Physical Education and Sports, Beijing, China.
Frontiers in psychiatry
|October 8, 2025
概括
运动干预显著减少双相情绪障碍 (BD) 患者的抑郁和焦虑症状. 然而,对躁狂症状的影响是不确定的,证据质量也很低.
科学领域:
- 心理健康 心理健康
- 运动科学 运动科学
- 临床心理学 临床心理学
背景情况:
- 双极性障碍 (BD) 是一种严重的精神健康状况,其特点是情绪波动.
- 运动越来越多地被探索为BD的补充疗法.
- 目前关于运动对BD症状有效性的证据需要进行系统评估.
研究的目的:
- 在BD患者中系统地审查和元分析运动干预措施对抑郁,躁狂和焦虑症状的疗效.
- 探索运动参数 (持续时间,频率,干预期) 如何影响症状结果.
- 评估BD运动干预措施的证据质量.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science等) 中进行全面搜索. 对于随机对照试验 (RCT).
- 纳入标准:患有BD的成年人 (≥18岁),作为初级干预措施的运动,标准护理控制.
- 使用PEDro尺度评估研究质量;使用Stata 18.0进行元分析;使用GRADE方法评估证据质量.
主要成果:
- 包括七个RCT (n=576) 在内. 在BD患者中,运动显著改善了抑郁症状 (SMD=-0.63) 和焦虑症状 (SMD=-0.70).
- 没有观察到对躁狂症状的显著影响 (SMD=-0.23).
- 亚组分析表明,较短的会议 (≤1小时),更高的频率 (>5/周) 和较短的干预期 (≤12周) 与更大的抑郁症状改善有关.
结论:
- 低质量的证据表明,运动可以减轻BD患者的抑郁和焦虑症状.
- 特定的运动方案 (高频,长时间,短期) 可能对抑郁症状更有效.
- 运动对躁狂症状的影响尚不清楚,由于研究的局限性,研究结果应谨慎解释.
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