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相关概念视频

Nomenclature of Aryl and Heterocyclic Amines01:10

Nomenclature of Aryl and Heterocyclic Amines

3.0K
The simplest aromatic amine is phenylamine, which contains an –NH2 functionality directly attached to an aromatic ring. The name aniline is designated for this skeleton. As shown in Figure 1, the common names of the functionalized anilines involve prefixes ortho-, meta-, and para- to indicate the substitution position. Different functionalized aniline derivatives also have notable trivial names.
3.0K
Amines to Sulfonamides: The Hinsberg Test01:23

Amines to Sulfonamides: The Hinsberg Test

4.4K
The Hinsberg test is a method to identify primary, secondary and tertiary amines, named after its pioneer, Oscar Hinsberg. Here, amines are treated with benzenesulfonyl chloride, also known as the Hinsberg reagent, in the presence of an excess of aqueous base, followed by acidification. Based on the nature of the amines, different changes are observed.
Generally, a primary amine reacts with the Hinsberg reagent to produce an N-substituted benzenesulfonamide. The electron-withdrawing sulfonyl...
4.4K
Basicity of Aromatic Amines01:18

Basicity of Aromatic Amines

8.0K
The basicity of aromatic amines is much weaker than that of aliphatic amines due to the involvement of the lone pair of electrons over the N atom in resonance with the aryl rings. Generally, the electron-donating ability of any substituents on the aryl ring of aromatic amines increases the basicity of the amine by increasing electron density, and hence the availability of lone pair on the nitrogen. On the other hand, electron-withdrawing functional groups on the aryl ring of amines decrease the...
8.0K
Physical Properties of Amines01:26

Physical Properties of Amines

4.1K
Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.
4.1K
Diazonium Group Substitution: –OH and –H01:19

Diazonium Group Substitution: –OH and –H

3.3K
Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
3.3K
Preparation of 1° Amines: Gabriel Synthesis01:28

Preparation of 1° Amines: Gabriel Synthesis

4.5K
Direct alkylation is not a suitable method for synthesizing amines because it produces polyalkylated products. Gabriel synthesis is the most preferred method to exclusively make primary amines. The method uses phthalimide, which contains a protected form of nitrogen that participates in alkylation only once to predominantly give primary amines.
Strong bases like NaOH or KOH deprotonate the phthalimide to form the corresponding anion, which acts as a nucleophile. Further, the anion attacks an...
4.5K

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相关实验视频

Updated: Jan 15, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Published on: January 19, 2016

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4-[(4-阿米诺--) 硫-]氨

Rao M Uppu1, Ogad A Agu2, Patrick F Mensah2

  • 1Department of Environmental Toxicology Southern University and A&M College Baton Rouge Louisiana 70813 USA.

IUCrData
|October 8, 2025
PubMed
概括
此摘要是机器生成的。

这项研究重新确定了C12H12N2S的晶体结构,揭示了尽管分子是无晶体的,但仍然具有性构造. 这些发现突出了硫桥梁.

关键词:
4,4′桥接的迪亚尼林.4,4′-西奥迪亚尼林的使用.晶体结构 晶体结构形状记忆的聚合物和玻璃材料.

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Facile Preparation of 4-Substituted Quinazoline Derivatives
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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科学领域:

  • 晶体学 晶体学是指结晶学.
  • 材料科学 材料科学 材料科学
  • 有机化学 有机化学

背景情况:

  • 化合物C12H12N2S之前已经研究过.
  • 了解分子构造和晶体包装对于材料设计至关重要.

研究的目的:

  • 为了重新确定C12H12N2S.的晶体结构.
  • 为了研究分子构成和晶体包装之间的关系.
  • 探索硫桥在分子间相互作用中的作用.

主要方法:

  • 低温 (100K) 单晶X射线衍射. 低温 (100K) 单晶X射线衍射. 低温 (100K) 低温 (100K) 低温 (100K) 低温 (100K) 低温 (100K) 低温) 低温 (100K) 低温 (100K) 低温 (100K) 低温) 低温 (100K) 低温 (100K)
  • 结构的完善. 结构的完善.
  • 分析分子间相互作用 (键,π相互作用).

主要成果:

  • 该结构得到了精细化,揭示了Sohncke空间组P212121.1.中的奇拉形状.
  • 乙烯基组之间的二面角被确定为72.01~7°.
  • 观察到一个3D结网络,涉及NH2替代物,硫原子,原子和π系统.

结论:

  • 阿基拉分子可以在固态中采用基拉形状.
  • 硫桥在指导晶体包装和分子间相互作用方面发挥着重要作用.
  • 这些发现对于调整聚合物设计中的包装相互作用具有重要意义.