第二次定位程序的"或错误"时代
Nicole Nelson1, Jennifer Den1, Roi Weiser2
1Department of Surgery, University of Texas Medical Branch, Galveston, Texas, USA.
The breast journal
|October 8, 2025
概括
光镜内科手术瘤检测 (FIND) 提供了比雷达 (R) 定位更准确的乳腺癌定位方法,降低了正边缘率. 这种技术消除了第二次手术,有可能改善患者的舒适度和手术结果.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 手术瘤学手术瘤学
背景情况:
- 活检后的剪辑通常远离原始瘤部位.
- 现有的定位方法,如雷达 (R) 定位,可能会增加这种距离.
- 光镜内科手术瘤检测 (FIND) 旨在在手术期间直接定位活检剪辑.
研究的目的:
- 评估FIND在手术内本地化方面的可行性.
- 为了比较FIND和R本地化之间的积极保证金利率.
- 评估局部精度对外科手术结果的影响.
主要方法:
- 进行部分乳房切除术的患者的回顾性审查 (2016年9月 - 2023年8月).
- R本地化和FIND组之间的结果比较.
- 使用毕达哥拉定理计算活检剪片和定位装置之间的距离.
主要成果:
- FIND 组: 3% 的正利率 (6/161) 与 R 组: 12% 的正利率 (7/55) (p=0.01).
- 对于R局部化 (p=0.09),正边缘病例 (19.1mm) 的平均距离比负边缘病例 (12.45mm) 更大 (p=0.09).
- 与R本地化相比,FIND显著降低了积极保证金利率.
结论:
- FIND是一种可行且有效的手术内定位技术.
- FIND显示的积极利率明显低于R本地化.
- 消除FIND的第二次局部化程序可能会改善无瘤边缘和患者体验.
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