案例报告:在氨酸寡腺细胞糖蛋白相关的视神经炎中发现 fundus 发现
John R Wilson1, Olivia W Cummings1, Matthew S Elitt1
1John F. Hardesty Department of Ophthalmology and Visual Sciences, Washington University in St.Louis School of Medicine, St. Louis, MO, United States.
Frontiers in ophthalmology
|October 8, 2025
概括
本案例研究详细介绍了一例罕见的髓寡细胞糖蛋白相关视神经炎 (MOG-ON) 病例,该病例在男性患者中表现为视网膜出血和罗斯斑. 早期诊断和治疗对于管理这种危及视力的疾病至关重要.
科学领域:
- 神经眼科神经眼科
- 脱线性疾病 脱线性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 髓寡腺细胞糖蛋白相关视神经炎 (MOG-ON) 是一种严重的脱髓化疾病,影响视力.
- MOG-ON的眼部表现是多样化的,但视网膜出血和罗斯斑点并不常见.
- 这项研究突出了MOG-ON.的独特呈现.
研究的目的:
- 在男性患者中报告一种罕见的双边MOG-ON病例,单边视网膜出血和罗斯斑点.
- 审查文献,以寻找与视网膜发现相似的MOG-ON发生情况.
- 强调在MOG-ON中承认多样化的脑膜镜检测结果的重要性.
主要方法:
- 一个48岁的男性患有急性视力丧失的病例报告.
- 镜检查,视神经成像和MOG抗体检测.
- 关于MOG-ON,视神经炎,视网膜出血和罗斯斑点的文学评论.
主要成果:
- 患者出现了双侧视神经,单侧视网膜出血和罗斯斑.
- 升高的MOG抗体证实了诊断.
- 使用类固醇和等离子体转化治疗导致显著的临床改善.
- 这是第三个报告的病例,也是第一例的男性MOG-ON与视网膜出血和罗斯斑点.
结论:
- 视网膜出血和罗斯斑,虽然很少见,但可以发生在MOG-ON.
- 识别这种多种背景镜检测结果对于及时诊断和管理至关重要.
- 及时治疗可以导致MOG-ON.的视力恢复.
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