在右慢性囊中风中,thalamic子场的改变大脑结构共变网络
Jun Guo1, Hongchuan Zhang2, Jingchun Liu3
1Department of Radiology, Tianjin Huanhu Hospital, Huanhu Hospital Affiliated to Tianjin Medical University and Tianjin University HuanHu Hospital, Tianjin, China.
Frontiers in neuroscience
|October 8, 2025
概括
慢性囊性中风会影响下子场灰色物质体积 (GMV) 网络. 这些变化影响了缩和缩的丘脑,揭示了广泛的网络变化.
科学领域:
- 神经成像是一种神经成像.
- 神经解剖学是一个神经解剖学.
- 脑卒中神经学 脑卒中神经学
背景情况:
- 丘陵体,一个关键的大脑结构,有广泛的连接和多样化的功能.
- 在慢性囊中风的背景下,其在子领域的灰质体积 (GMV) 协变网络尚未得到充分理解.
研究的目的:
- 为了调查 GMV 共变网络的乳头子场是否在慢性囊性中风患者中受到选择性的影响.
- 为了确定特定的胸膜子场及其中风后的网络变化.
主要方法:
- 招募了45名患有慢性右囊中风 (CS) 的患者和93名正常对照 (NC).
- 使用FreeSurfer将丘脑细分为25个子领域.
- 应用了通用线性模型来比较CS和NC组之间的GMV协差网络,纠正混.
主要成果:
- 所有25个ipsilesional thalamic子场都显示了CS患者的缩.
- 十六个化体的thalamic子场表现出改变的GMV协同变异连接与各种大脑区域.
- 3个受损thalamic子场显示了改变的GMV共变连接与ipsilesional区域.
结论:
- thalamic子场的GMV共变网络选择性地参与慢性囊性中风.
- 这些网络变化影响了缩和缩的乳头子场.
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