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破解密码:piRNA途径如何塑造精子生成并对抗男性不孕症

Zhidan Hong1,2,3, Sihan Huang1,4, Li Li1

  • 1Center for Reproductive Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.

Frontiers in cell and developmental biology
|October 8, 2025
PubMed
概括

与PIWI相互作用的RNAs (piRNAs) 通过调节精子发育和基因组完整性,对男性生育至关重要. 在piRNA路径中发生的干扰会导致不孕,为男性生殖健康提供新的诊断和治疗点.

关键词:
在PIWI蛋白质中.表观遗传调节 表观遗传调节男人的不孕不育症.这就是piRNA生物标志物.精子的产生是精子的产生.可转移的元素可以转移.

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