新型皮肤脉冲式心室辅助装置 (PulseCath) 的临床和临床前证据:一个范围审查
Viviana Teresa Agosta1, Jacopo D'Andria Ursoleo1, Corrado D'Andria2,3
1Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Artificial organs
|October 8, 2025
概括
脉冲式心室辅助装置PulseCath提供了对心脏性休克的中间支持. 需要进一步的研究来确定这种临时机械循环支持 (tMCS) 装置的最佳患者群体.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 血液动力学 血液动力学
背景情况:
- 临时机械循环支持 (tMCS) 越来越多地用于心脏性休克.
- PulseCath是一种脉动性心室辅助设备,在IABP和更具侵入性的设备之间提供中间支持.
- 它可能会解决对特定患者群体的TMCS尚未满足的需求.
研究的目的:
- 系统地审查有关PulseCath植入的现有临床和临床前数据.
- 评估PulseCath设备的当前使用情况和初步发现.
主要方法:
- 在主要的生物医学数据库 (PubMed/MEDLINE,EMBASE,Cochrane,Web of Science,Scopus,Google Scholar) 进行系统的文献搜索.
- 包括临床前体内研究和临床研究报告PulseCath植入数据.
主要成果:
- 确定了五项临床前研究 (38只动物) 和16项临床研究 (386名患者).
- PulseCath主要用于高风险皮肤冠状动脉干预期间的预防性治疗.
- 在血液动力学不稳定性中也报告了救助使用.
结论:
- 初步发现表明PulseCath易于使用,但报告不足限制了最终的评估.
- 需要进一步的研究来确定特定的患者群体受益于PulseCath.
- 整合病理生理学数据和强大的临床研究可以扩大其应用.
相关概念视频
Pulse
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
Pulse amplitude and quality
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Pulse rhythm
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Pulse Assessment Sites
Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
Pulse
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
The pulse serves as a clinical indicator...
Cardiac Catheterization II: Right Heart Catheterization
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...


