直肠拭子培养在经过直肠前列腺活检后的感染并发症中的作用
Naveen Kumar Gupta1, Kamalakanta Beheruk2, Debansu Sarkar2
1Department of Urology, Medical College and Hospital, Kolkata, WB, India.
Urologia
|October 8, 2025
概括
基于直肠拭片培养的向抗生素预防显著减少前列腺活检后的传染性并发症. 这种方法优于实证抗生素,原因是直肠生物体的高诺基诺隆耐药率.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 通过直肠超声波引导的前列腺活检与传染性并发症有关.
- 经验性抗生素预防是常用的,但由于抗菌素耐药性增加,可能是无效的.
研究的目的:
- 为了评估直肠拭子培养引导的向抗菌预防在预防前列腺活检后的传染性并发症的有效性.
- 为了比较针对性预防与标准的经验性抗生素预防.
主要方法:
- 一项前性观察性研究比较了针对性预防 (基于识别诺基诺抗性的直肠拭子培养) 与经验性预防.
- 在接受过直肠超声导向前列腺活检的患者中,在活检后30天内评估了感染性并发症.
主要成果:
- 48%的患者在直肠培养中存在耐诺的生物.
- 针对性预防组的感染并发症显著减少 (6%比12%),包括尿路感染和发烧.
- 败血症发生在接受经验预防的患者中的4%,在向组中没有任何患者.
结论:
- 高水平的诺基诺隆耐药性使得标准的经验性预防不适合前列腺活检.
- 以直肠拭子培养为指导的向抗生素预防有效地减少了活检后的传染性并发症.
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