Jove
Visualize
联系我们

相关概念视频

Synthetic Biology02:55

Synthetic Biology

5.5K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.5K
Recombinant DNA01:09

Recombinant DNA

101.6K
Overview
101.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

New targets and procedures for validating the valence geometry of nucleic acid structures.

Nucleic acids research·2026
Same author

NMR-based conformational analysis of DNA G-quadruplex guides mapping essential structure-function relationship in protein chaperoning.

Physical chemistry chemical physics : PCCP·2026
Same author

Catalyzing Protein Folding by Chaperones.

Biology·2025
Same author

Halogen bonds between ligands and proteins: Can we use them in validation?

Protein science : a publication of the Protein Society·2025
Same author

DSSP 4: FAIR annotation of protein secondary structure.

Protein science : a publication of the Protein Society·2025
Same author

Quantitative Thermodynamic Characterization of Self-Assembling RNA Nanostructures.

bioRxiv : the preprint server for biology·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Jan 15, 2026

Electron Cryotomography of Bacterial Cells
14:23

Electron Cryotomography of Bacterial Cells

Published on: May 6, 2010

26.2K

在视频游戏玩家的帮助下重建生物分子.

Andreas C Petrides1, Robbie P Joosten2, 3

  • 1Department of Computer and Information Science, University of Massachusetts Dartmouth, Dartmouth, Massachusetts, USA.

Acta crystallographica. Section D, Structural biology
|October 8, 2025
PubMed
概括

玩Foldit电子游戏的公民科学家在蛋白质数据库 (PDB) 中显著改进了蛋白质模型. 他们的贡献通过PDB-REDO数据库增强了结构生物学记录,证明了公众对科学参与的价值.

关键词:
把它折叠起来.这是PDB-REDO.公民科学是公民科学.模型的策划策划.

更多相关视频

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
12:49

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells

Published on: September 28, 2019

13.3K
Modeling an Enzyme Active Site using Molecular Visualization Freeware
14:37

Modeling an Enzyme Active Site using Molecular Visualization Freeware

Published on: December 25, 2021

11.3K

相关实验视频

Last Updated: Jan 15, 2026

Electron Cryotomography of Bacterial Cells
14:23

Electron Cryotomography of Bacterial Cells

Published on: May 6, 2010

26.2K
A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells
12:49

A Method for 3D Reconstruction and Virtual Reality Analysis of Glial and Neuronal Cells

Published on: September 28, 2019

13.3K
Modeling an Enzyme Active Site using Molecular Visualization Freeware
14:37

Modeling an Enzyme Active Site using Molecular Visualization Freeware

Published on: December 25, 2021

11.3K

科学领域:

  • 结构生物学是结构生物学.
  • 计算生化学计算生化学
  • 公民科学是公民科学.

背景情况:

  • 蛋白质数据库 (PDB) 是对实验性蛋白质结构模型的公共存储库.
  • 准确的蛋白质模型对于理解生物功能和开发治疗方法至关重要.
  • 公民科学倡议可以为复杂的科学问题提供众包解决方案.

研究的目的:

  • 引入和评估一系列新的Foldit拼图,旨在提高PDB中的蛋白质模型的准确性.
  • 建立一个机制,将Foldit玩家的贡献纳入官方结构生物学记录.
  • 评估公民科学对蛋白质结构数据质量的影响.

主要方法:

  • 专业的Foldit拼图的开发专注于提炼蛋白质模型.
  • 分析球员表现和结构性改进的程度.
  • 将Foldit衍生精细模型集成到PDB-REDO数据库中进行验证和传播.

主要成果:

  • Foldit玩家成功地提高了PDB中沉积的蛋白质结构的准确性.
  • 拟议的机制有效地将参与者的贡献引入科学记录.
  • 公民科学家精制的蛋白质模型的质量得到了显著的改善.

结论:

  • 公民科学,以Foldit为例,提供了一种强大的方法来提高结构生物学数据的质量.
  • 将公民科学工作集成到PDB-REDO等数据库中,有助于提高科学可重复性和数据完整性.
  • 让公众参与诸如蛋白质建模等科学事业,对于科学进步至关重要.