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随机最佳选择设计用于剂量优化

Shuqi Wang1, Ying Yuan1, Suyu Liu1

  • 1Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.

Biometrics
|October 8, 2025
PubMed
概括

美国食品和药物管理局 (FDA) 的目标是选择最佳的生物剂量 (OBD). 一个新的随机最佳选择 (ROSE) 设计将患者样本大小最小化,以实现准确的OBD识别.

关键词:
剂量优化剂量优化最优的设计最优的设计随机化是一种随机化.选择设计设计的选择.

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