性别确认激素治疗对年轻人的代谢影响
Jeremy Winer1, Maya McKee2, Michelle B Lemelman1
1Section of Endocrinology, Diabetes and Metabolism, Chicago, Illinois.
Pediatric annals
|October 8, 2025
概括
跨性别和性别多样性 (TGD) 青年可能面临不同的代谢健康风险. 本综述探讨了性别肯定性激素治疗 (GAHT) 对TGD青少年和年轻成年人代谢健康的影响.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 青少年医学 青少年医学
背景情况:
- 与 cisgender 同龄人相比,跨性别和性别多样性 (TGD) 的年轻人表现出不同的代谢状况率.
- 心理健康,少数群体压力和行为显著影响这些代谢差异.
- 性激素 (雌激素,) 对性二态代谢健康模式至关重要.
研究的目的:
- 审查接受性别肯定激素治疗 (GAHT) 的青少年和年轻成年人的代谢变化.
- 评估GAHT对心血管健康,脂质代谢,胰岛素抵抗,身体组成和肝功能的影响.
- 总结基线代谢特征,预期的GAHT相关变化和查建议.
主要方法:
- 对TGD年轻人GAHT和代谢健康的新兴研究进行系统审查.
- 对5个关键代谢领域的研究进行评估.
- 对基线数据,治疗引起的变化和当前查指南的分析.
主要成果:
- 总结了在GAHT之前的TGD年轻人的基线代谢概况.
- 描述了在GAHT期间在心血管,脂质和胰岛素抵抗领域观察到的代谢变化.
- 审查与GAHT相关的身体组成和肝功能变化.
结论:
- GAHT可以影响TGD青少年和年轻成年人的代谢健康.
- 了解这些代谢变化对于监测和管理至关重要.
- 基于指南的查对于在GAHT期间的代谢健康监测至关重要.
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