校正:解热化韩国大米葡萄酒 (Makgeolli) 对肠道功能和肠道活动在小鼠的洛佩拉胺诱导的便秘的影响
Soyoung Jung1, Yunjung Lee2, Yoo Kyoung Park1
1Department of Medical Nutrition, AgeTech-Service Convergence Major, Kyung Hee University, Yongin 17104, Republic of Korea. ypark@khu.ac.kr.
Food & function
|October 8, 2025
概括
软化韩国大米葡萄酒 (Makgeolli) 改善了小鼠的肠道功能和肠道活动,这些小鼠患有洛佩拉胺诱导的便秘. 这项研究强调了Makgeolli.
科学领域:
- 胃肠病学和食品科学 胃肠病学和食品科学
背景情况:
- 便秘是一种常见的胃肠道疾病.
- 洛佩拉胺诱导的老鼠便秘是研究抗便秘作用的标准模型.
- 韩国米酒 (Makgeolli) 是一种传统的发酵饮料,具有潜在的健康益处.
研究的目的:
- 调查韩国冷解水酒 (Makgeolli) 对肠道功能和肠道活动的影响.
- 评估Makgeolli在减轻小鼠模型中洛佩拉胺诱导的便秘的疗效.
主要方法:
- 通过使用洛佩拉米德诱导大鼠便秘.
- 不同剂量的冷化麦吉奥利给了老鼠.
- 评估了肠道过渡,便输出和相关的生物化学标志物.
主要成果:
- 淋化马克吉奥利显著改善了便秘大鼠的肠道过渡时间.
- 在Makgeolli给药后,便产量增加.
- 观察到特定的肠道微生物群变化,这表明在观察到的效应中发挥了作用.
结论:
- 软化韩国大米葡萄酒 (Makgeolli) 显示对便秘有治疗作用.
- 麦吉奥利可以作为一种功能性食品成分,改善肠道健康并缓解便秘.
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