相关实验视频

Updated: Jan 15, 2026

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis

Published on: March 4, 2014

肢体结是ALS进展的预测因素:一项超声波研究

Nan Hu¹, Ming Qi¹, Huihong Tian¹

¹Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100730, China.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

|October 8, 2025

概括

超声波检测到的肌性侧面硬化症 (ALS) 中的粘膜预测了疾病的进展. 较高的囊分数与功能和力量的更快下降相关,有助于预后判断.

科学领域:

神经学神经学
生物医学成像技术生物医学成像技术
临床研究临床研究

背景情况:

肌缩侧面硬化症 (ALS) 是一种进展性神经退行性疾病.
预测ALS进展对于患者管理和临床试验至关重要.
,肌肉抽,是常见的ALS症状之一.

研究的目的:

为了研究超声波识别ALS的结的预测价值.
为了与ALS进展率相关联结症的严重程度.
探索结作为一种潜在的生物标志物来预测ALS的预后.

主要方法:

招募散发性ALS患者进行3-6个月的随访.
使用肌肉超声波 (总纤维化得分) 评估纤维化严重程度.
收集的基线和随访ALS功能评级尺度修订 (ALSFRS-R) 评分和肌肉力量.

主要成果:

总囊积分与ALSFRS-R进展率正相关 (p<0.001).
较低的囊分数表明快速ALSFRS-R进展的风险明显较低 (HR 0.132).
肌肉具有高度的结显示显著更高的强度下降率 (p<0.001).

结论:

关节的严重程度预测ALSFRS-R的下降和肌肉力量的损失.
超声波检测到的块可以作为ALS进展的生物标志物.
研究结果支持在预后判断和临床试验分层中使用粘膜.

关键词:

肌缩性侧面硬化症 (AMLS) 是一种疾病.这些都是"Fasciculations".一个进步的进步.超声波超声波是指超声波的使用.

更多相关视频

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration

Published on: June 15, 2018

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Published on: January 11, 2019

相关概念视频

Ultrasound II: Endoscopic Ultrasound and FibroScan

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...