皮肤性并发症与亚托匹性皮肤炎相关 走向共同的治疗方法:叙述性综述
Maria Esposito1, Alessandro Giunta2, Andrea De Berardinis1
1Dermatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Vetoio-Coppito 2, 67100, L'Aquila, Italy.
Dermatology and therapy
|October 8, 2025
概括
亚托皮炎 (AD) 通常与其他皮肤疾病同时发生,使治疗复杂化. 通过使用向治疗来识别和管理这些皮肤相关疾病,可以显著改善患者的治疗结果.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
背景情况:
- 亚托皮炎 (AD) 是一种慢性炎症性皮肤疾病.
- 阿尔茨海默病经常伴随其他皮肤病,影响患者的管理和治疗成功.
研究的目的:
- 审查与亚托皮性皮肤炎相关的皮肤相关疾病.
- 分析它们的潜在机制和临床实践中的治疗影响.
主要方法:
- 进行了叙事审查.
- 搜索了包括PubMed,Embase,Cochrane和ClinicalTrials.gov.gov在内的数据库.
- 用于阿尔茨海默病及其常见的并发症的搜索术语.
主要成果:
- 在阿尔茨海默病和诸如过敏性接触性皮肤炎,大发性脱发症,牛皮等疾病之间发现了强烈的联系.
- 雅克抑制剂,dupilumab和生物药物在治疗多种并发性疾病方面表现有前途.
结论:
- 识别AD的并发症对于有效的患者管理至关重要.
- 针对阿尔茨海默病及其并发症的共享免疫路径的量身定制疗法可能会改善结果.
- 为了优化治疗策略和组合疗法,需要进一步的研究.
相关概念视频
Changes in Skin Color: Clinical Perspectives
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Asthma: Pathogenesis and Management
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-IV: Diagnostic and Management
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Acne Infection
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...


