饮食模式对婴儿成长的影响:一项用肠道微生物群洞察力的纵向研究
Vidya Rajesh1, Asha Hegde2, Mamatha Ballal3
1Department of Pediatrics, Manipal Academy of Higher Education (MAHE), Melaka Manipal Medical College, Manipal, Karnataka, India.
Indian pediatrics
|October 8, 2025
概括
纯母乳养支持健康的婴儿肠道微生物群和发育. 混合养模式与婴儿超重和传染病的增加有关.
科学领域:
- 儿童营养学 儿童营养学
- 婴儿肠道微生物组 婴儿肠道微生物组
- 发育儿科 发育儿科
背景情况:
- 婴儿养习惯显著影响健康结果.
- 了解肠道微生物组在婴儿发育中的作用至关重要.
- 关于各种养模式对婴儿健康和肠道微生物群的长期影响的数据有限.
研究的目的:
- 为了确定纯母乳养的流行情况.
- 评估婴儿养模式对生长,感染和发育的影响.
- 分析肠道微生物组的组成和多样性与养模式的关系.
主要方法:
- 对374名健康新生儿及其母亲进行前性队列研究.
- 在出生和1.5,3.5,6,9和12个月时收集的养数据.
- 通过便样本进行肠道微生物组分析,分别是出生时,1.5岁,3.5岁和9个月.
主要成果:
- 在12个月的混合养组中观察到更高的超重患病率 (P=0.019).
- 混合补充养与9个月后增加抗生素暴露 (P=0.002) 和发烧 (P=0.009) 和腹 (P=0.024) 等感染有关.
- 肠道微生物群由Firmicutes主导,随着年龄的增长,Bifidobacterium和Streptococcus属的丰富性越来越大.
结论:
- 哺乳促进有益的肠道细菌和微生物多样性.
- 在家庭进行补充养时,与更好的营养状况和更少的感染有关.
- 婴儿养选择对肠道健康和整体福祉有重大,可衡量的影响.
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