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Updated: Aug 3, 2026

Folding and Characterization of a Bio-responsive Robot from DNA Origami
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作为TLR9激动剂的DNA纳米结构的理性设计

Chunfa Chen1, Cheng Tian1, Zhuoer Jin1

  • 1College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.

Biomacromolecules
|October 8, 2025
PubMed
概括

DNA纳米结构为设计用于免疫治疗的托尔类受体9 (TLR9) 激动剂提供了一种新的方法. 优化连接体定向和结构寡合化增强TLR9的激活,为改进的癌症和疫苗疗法铺平了道路.

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RNA Structure01:23

RNA Structure

Overview
The basic structure of RNA consists of a five-carbon sugar and one of four nitrogenous bases. Although most RNA is single-stranded, it can form complex secondary and tertiary structures. Such structures play essential roles in the regulation of transcription and translation.
Different Types of RNA Have the Same Basic Structure
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Types of RNA01:23

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Overview
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CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
RNA Structure01:19

RNA Structure

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DNA Structure
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