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心内心声谱与食管内心声谱在心房移除中:一项随机临床试验
Xiaofeng Hu1, Weifeng Jiang1, Xinhua Wang2
1Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
JAMA cardiology
|October 8, 2025
概括
心脏内心回声学 (ICE) 与食道内心回声学 (TEE) 不相差,用于预防心房动 (AF) 移除期间发生的血栓栓塞事件. 此外,ICE还证明了提高了安全性,效率和患者舒适度.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 干预程序 干预程序
背景情况:
- 过食管回声心电图 (TEE) 是在心房动 (AF) 移除前进行血栓查的标准,但存在程序性风险.
- 心内回声心脏成像 (ICE) 是一种具有潜在的安全性和程序优势的替代成像方式.
研究的目的:
- 为了评估ICE是否与TEE在预防经过AF切除的患者周围手术性血栓栓塞事件方面不劣.
- 为了比较ICE和TEE之间的安全性,效率和患者舒适性,用于AF移除血栓查.
主要方法:
- 一个多中心随机临床试验,涉及1810名预定进行导管切除的AF成年患者.
- 患者被随机分配,通过ICE (n=906) 或TEE (n=904) 进行血栓查.
- 主要终点是周围程序性血栓栓塞事件的发生率;次要终点包括血栓检测,安全性,效率和患者舒适性.
主要成果:
- 血栓塞栓事件发生在ICE的0.4%与TEE的0.6%之间 (Pnoninferiority=.01),表明非劣势.
- ICE显示,与穿越性穿刺相关的大型出血的发生率显著降低 (0.2%对1.2%,P=.03).
- 与TEE相比,ICE减少了光镜时间,手术前的等待时间,以及患者报告的焦虑或抑郁.
结论:
- 心内回声扫描 (ICE) 是通过食道回声扫描 (TEE) 的安全和有效替代品,用于在AF切除中血查.
- 在程序安全,效率和患者舒适性方面,ICE提供了显著的优势,支持其在临床实践中的采用.
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