介绍评估流行病学跨国可转移性的描述性框架:在两个欧洲国家之间推断儿科限制生命条件的流行情况的应用
Larissa Kubek1,2, Julia Wager1,2,3, Patrick Brzoska4
1PedScience Research Institute, Datteln, Germany.
Journal of palliative medicine
|October 8, 2025
概括
一个新的框架,FACT,使得可靠的传输国家之间的儿科生命限制条件的流行率数据. 这种方法成功地估计了超过10万名受这种情况影响的德国儿童.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 儿科健康 儿科健康
背景情况:
- 在信息有限的国家之间传输流行病学数据是具有挑战性的.
- 跨国应用儿科生命限制性疾病 (LLC) 患病率缺乏标准化的方法.
- 现有的跨国数据传输方法是无结构的,需要验证.
研究的目的:
- 引入评估流行病学跨国可转移性的描述性框架 (FACT).
- 为验证和执行传输流行病学流行率估计提供一个系统的五步方法.
- 评估从英格兰到德国的儿科LLC流行数据的可转移性.
主要方法:
- 将FACT框架应用于德国儿科人口数据,以英语流行率估计为基础.
- 根据年龄和性别,对英格兰和德国的官方人口统计数据进行了调整.
- 两国之间的关键流行病学指标进行比较,以评估可转移性.
主要成果:
- 英格兰和德国之间的比较指标显示出最小的偏差 (<2.5/5个百分点),支持数据传输.
- 据估计,在2022年,约有103,566名德国儿童和青少年 (每10,000人中有65.30) 受到缩短生命的疾病的影响.
- 预测显示到2030年,病例将在107,934至138,817之间.
结论:
- 据了解,FACT框架是将流行病学流行病数据跨越国界的有价值工具.
- 该研究成功地证明了FACT在估计德国儿科生命限制条件中的有用性.
- FACT的适用性很可能可以扩展到其他流行病学措施,包括发病率.
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