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Updated: Jan 15, 2026

Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules
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ASPL将应力颗粒的组装与其VCP介导的拆卸相结合

Gautam Pareek1, Dongfang Li1, Bo Wang2,3

  • 1Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

Science advances
|October 8, 2025
PubMed
概括

膜软部肉瘤位点 (ASPL) 通过调节G3BP凝结和VCP激活来连接应力颗粒 (SG) 的组装和拆卸. 在ASPL-VCP相互作用中出现的干扰可能会导致神经退行性疾病.

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