相关实验视频

Updated: Jan 15, 2026

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

Confocal Imaging of Confined Quiescent and Flowing Colloid-polymer Mixtures

Published on: May 20, 2014

聚合物度在共流的亚微粒子粘弹性分离中的作用

Samith Hettiarachchi¹, Dan Yuan², Nam-Trung Nguyen¹

¹Queensland Quantum and Advanced Technologies Research Institute, Griffith University, Nathan, Queensland, 4111, Australia; School of Engineering and Built Environment, Griffith University, Nathan, Queensland, 4111, Australia.

|October 8, 2025

概括

粘弹性微流体中的高聚合物度使新型颗粒分离成为可能. 这项研究表明,特定的高聚乙烯氧化物 (PEO) 度可以逆转粒子迁移,允许有效分离100nm和500nm粒子.

科学领域:

生物技术和诊断生物技术和诊断
微流体学微流体学
非牛顿流体动力学的流体动力学.

背景情况:

微小粒子操纵,包括细胞外囊泡 (EV),病毒和细菌,对于生物技术和诊断至关重要.
粘弹性微流体技术在非牛顿式流体中提供高分辨率的粒子分类,并流系统是一个流行的设计.
目前关于粘弹性流体中颗粒分离的研究主要研究低度的聚合物,使高度的影响在很大程度上未被探索.

研究的目的:

通过使用高度的聚乙烯氧化物 (PEO) 在粘弹性共流微流体系统中研究100nm和500nm粒子的迁移行为.
探索PEO度,流量比率 (FRR) 和总流量对粒子迁移和平衡位置的影响.
为了证明观察到的现象对有效的亚微粒颗粒混合物分离的应用.

主要方法:

使用高度聚乙烯氧化物 (PEO) 的粘弹性共流微流体系统.
研究了100nm和500nm粒子在不同PEO度 (样本和流),FRR和总流速下的迁移.
应用了优化条件来分离亚微米粒子的二元混合物.

主要成果:

在低PEO度下,较大的 (500nm) 粒子比较小的 (100-nm) 粒子更快地迁移到中心.
在特定的高PEO度下,观察到逆向迁移:小颗粒 (100-nm) 聚焦在中心,而大颗粒 (500-nm) 停留在侧壁附近.
在二进制混合物分离中,在100纳米颗粒中达到88%的分离纯度,在500纳米颗粒中达到87%.

结论:

在粘弹性共流系统中高聚合物度可以逆转粒子迁移行为.
调整高PEO度为优化基于尺寸的亚微米粒子分离提供了一种新的策略.
这种方法对生物技术和诊断领域的应用具有重大潜力,这些应用需要精确的粒子操纵.

关键词:

同流的微流体系统高聚合物的高度聚合物.亚微米粒子分离器的分离方法粘性弹性微流体聚焦器

更多相关视频

Solution Blow Spinning of Polymeric Nano-Composite Fibers for Personal Protective Equipment

Solution Blow Spinning of Polymeric Nano-Composite Fibers for Personal Protective Equipment

Published on: March 18, 2021

Molecular Entanglement and Electrospinnability of Biopolymers

Molecular Entanglement and Electrospinnability of Biopolymers

Published on: September 3, 2014

相关概念视频

Polymers: Molecular Weight Distribution

Polymers: Molecular Weight Distribution

For any given polymer, the weight average molecular weight (Mw) is higher than, if not equal to, the number average molecular weight (Mn). The only situation in which the weight average molecular weight and the number average molecular weight are equal is when a polymer consists only of chains with equal molecular weight. However, this never happens in a synthetic polymer, since it is difficult to control the polymerization process up to a molecular level with accuracy to a hundred percent.

Viscosity

Viscosity

When water is poured into a glass, it falls freely and quickly, whereas if honey or maple syrup is poured over a pancake, it flows slowly and sticks to the surface of the container. This difference in the flow of different kinds of liquids arises due to the fluid friction between the liquid layers and the liquid and the surrounding material. This property of fluids is called fluid viscosity. In this example, water has a lower viscosity than honey and maple syrup.
The SI unit of viscosity is...

Colloids and Suspensions

Colloids and Suspensions

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...