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酸盐激酶M2 (PKM2) 通过通过Akt/mTOR通路调节糖解重编程来调节类风湿性关节炎

Hai-Yang Liao1, Guo-Hua Zhang2, Jian-Xiong Zheng1

  • 1The Second Clinical Medical College of Lanzhou University, Lanzhou 730000, PR China; Department of Rheumatology, Lanzhou University Second Hospital, Lanzhou 730000, PR China.

The international journal of biochemistry & cell biology
|October 8, 2025
PubMed
概括

酸激酶M2 (PKM2) 通过促进突细胞中的葡萄糖代谢来驱动类风湿性关节炎 (RA) 的炎症. 抑制PKM2可以降低RA症状和关节损伤,这表明它可以.

关键词:
纤维细胞类的突细胞.炎症反应是一种炎症反应.病理性糖溶解是一种病理性糖溶解.酸盐激酶M2 (PKM2) 是一种酸盐激酶.类风湿性关节炎 (RA) 是一种

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