老年人发病的阴性脑粉样性血管病变,呈现为叶状和深层出血
Hiroki Sakamoto1, Aya Murakami2, Yumiko Kono3
1Neurology, Kansai Medical University, Hirakata, Osaka, Japan.
BMJ case reports
|October 8, 2025
概括
一个罕见的病例表明,阳性脑粉样性血管病变 (CAA) 可能被误诊为高血压出血. 这凸显了在复发性脑内出血中考虑阳性原因的重要性,即使在老年患者中也是如此.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 放射学 放射学是一门学科.
背景情况:
- 经常性脑内出血 (ICH) 可能源于各种原因,包括血管形和高血压.
- 大脑粉样血管病变 (CAA) 是自发性叶片性ICH的常见原因,通常影响55岁以上的人.
- 阳性CAA是一种不太常见的形式,通常与先前的神经外科手术和硬膜移植有关,通常在年轻患者中见到.
研究的目的:
- 报告一次性复发性ICH病例,该病例发生在被诊断患有阳性CAA的老年患者身上.
- 探索错误地将阳性CAA归类为高血压出血的诊断挑战和影响.
主要方法:
- 一个60多岁的男性患有复发性ICH病例报告.
- 对患者病史的审查,包括先前的下关节出血和动脉瘤剪切.
- 诊断工作包括PET/CT用于粉样蛋白和遗传分析.
- 差异诊断考虑高血压的ICH和阳性CAA.
主要成果:
- 患者出现了复发性ICH,尽管没有血管风险因素.
- 根据神经外科病史和粉样蛋白PET/CT检测结果,诊断出阳性CAA,尽管患者55岁以上.
- 甲状腺出血的位置构成了诊断挑战,因为它是CAA的非典型.
结论:
- 这一案例表明,即使在老年人中,在复发性ICH的差异诊断中,应考虑催产素CAA,即使在老年人中.
- 一些被诊断为高血压脑出血的病例实际上可能是阳性CAA.
- 对于脑出血的准确诊断和管理来说,对阳性原因的认识至关重要.
更多相关视频
相关概念视频
Alzheimer's Disease: Overview
1.6K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K
Aneurysm II: Clinical Manifestations and Diagnostic Studies
293
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
293


