加拿大推进艾滋病毒暴露前预防 (PrEP) 实施:对计划,实践和政策的范围审查协议
Debapriya Chakraborty1, Pascal Djiadeu2, Carolyn Ziegler3
1Reach NEXUS, MAP Centre for Urban Health Solutions, Unity Health Toronto, Toronto, Ontario, Canada debapriya.chakraborty@unityhealth.to.
BMJ open
|October 8, 2025
概括
本范围审查审查审查了改善加拿大艾滋病毒暴露前预防 (PrEP) 采用的干预措施. 它确定了提高高风险人群意识,获取和持续使用的战略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 艾滋病毒暴露前预防 (PrEP) 显著降低了艾滋病毒感染风险,但在加拿大面临不理想的吸收.
- 诸如耻辱,成本和医疗保健等障碍阻碍了PrEP的使用,特别是在高风险群体中.
- 有针对性的干预措施对于提高PrEP的接受,获取和持续使用至关重要.
研究的目的:
- 对旨在增加加拿大艾滋病毒prep接受,获取,吸收和持续使用的干预措施进行范围审查.
- 绘制现有计划,实践和政策的范围和类型.
- 为未来的研究和政策制定提供信息,以改善PrEP的实施.
主要方法:
- 使用乔安娜·布里格斯研究所 (JBI) 范围审查方法.
- 进行全面的数据库搜索 (MEDLINE,Embase,PsycINFO等) 从2016年开始.
- 两位独立审查员选了研究,提取了数据,并在加拿大背景下综合了研究结果.
主要成果:
- 审查将识别和分类针对PrEP意识,接受,访问,吸收和持续使用的干预措施.
- 结果将使用系统审查和元分析 (PRISMA) 首选报告项目流程图来呈现.
- 提取的数据将被总结为指导未来的战略.
结论:
- 这一综述将提供加拿大PrEP干预措施的全面概述.
- 它旨在突出成功的策略,并确定当前方法中的差距.
- 这些发现将支持基于证据的政策和实践,以优化PrEP在艾滋病毒预防中的作用.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
3.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.6K
Retrovirus Life Cycles
49.3K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
49.3K
Primary Healthcare Services
1.9K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.9K
Levels of Health Promotion and Illness Prevention
14.2K
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
14.2K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
406
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
406
Preclinical Development: Overview
5.8K
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
5.8K


