辅助的中医草药与PCI后针相比:比较有效性和安全性 - - 系统审查和网络元分析协议
Yongxing Dai1, Yang Jiao2, Yibin Xu1
1Siyang County Traditional Chinese Medicine Hospital, Siyang, China.
BMJ open
|October 8, 2025
概括
本系统性审查评估了中国草药 (CHM) 或针作为皮肤冠状动脉干预 (PCI) 后患者的附加疗法. 它综合了与标准护理相比,它们的有效性和安全性的证据.
科学领域:
- 心脏病学 心脏病学
- 综合医学是一个整体的医学.
- 证据综合 证据综合
背景情况:
- 冠状动脉疾病 (CAD) 仍然是全球主要的健康问题.
- 穿皮冠状动脉干预 (PCI) 改善了结果,但残留风险仍然存在.
- 中国草药 (CHM) 和针是PCI后常见的辅助疗法,特别是在东亚.
研究的目的:
- 在PCI后的成年患者中,系统地审查CHM或针与标准护理相结合的疗效和安全性,与单独的标准护理相比.
- 如果网络元分析是可行的,可以直接比较CHM和针.
主要方法:
- 对平行组随机对照试验 (RCT) 的系统审查和元分析 (对照和网络).
- 在没有语言限制的情况下搜索主要的国际和中国数据库和试验注册表.
- 使用Cochrane RoB 2工具对偏见风险的评估以及使用GRADE方法对证据的确定性.
主要成果:
- 数据的提取和合成将由两个独立的审查员进行.
- 结果包括主要不良心血管事件 (MACE),死亡率,心痛得分和与健康有关的生活质量 (HRQoL).
- 双对元分析将使用随机效应模型;网络元分析将比较CHM与针.
结论:
- 这一审查将提供综合证据,证明将CHM或针整合到标准PCI后护理中的有效性和安全性.
- 结果将为临床实践和未来的研究方向提供信息,用于CAD管理的补充疗法.
- 该研究遵循道德准则,没有直接的人体实验.
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