介绍患者关于nocebo效应的干预措施:对当前证据的系统审查
Emily K Spotts1, Andrew L Geers1
1Department of Psychology, University of Toledo, Toledo, OH 43606, United States.
概括
诺塞博教育,即向个人提供关于诺塞博效应的信息,显示了减少负面副作用的初步承诺. 需要进一步的研究,特别是在患者群体中,以确认其对减轻症状的影响.
科学领域:
- 心理学 心理学 心理学
- 医学教育 医学教育
- 健康科学 卫生科学 卫生科学
背景情况:
- 披露副作用信息可能会引发nocebo副作用,对健康和治疗坚持产生负面影响.
- 诺塞博的副作用降低了生活质量,需要进行干预以减轻它们的发生.
- 诺塞博教育,即向个人提供关于诺塞博效应的信息,是潜在的干预策略.
研究的目的:
- 系统地审查和评估关于nocebo教育作为干预措施的研究.
- 总结nocebo教育在减少nocebo副作用方面的有效性.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在PubMed,Web of Science和PsychInfo数据库中进行的搜索.
- 包括操纵nocebo教育的受控实验.
主要成果:
- 确定了18个记录,其中有21项关于nocebo教育的研究.
- 在患者 (5/6研究) 和非患者 (11/15研究) 样本中,nocebo教育表明了症状和/或心理变化.
- 在不同研究中,效果大小差异很大.
结论:
- 初步证据支持nocebo教育能够减少副作用并影响nocebo效应机制.
- 目前的文献有限,强调需要更多的研究,特别是患者样本.
- 需要进一步的研究来优化nocebo教育干预措施,并解决相互矛盾的结果.
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