一个多中心随机对照试验的门诊与住院患者皮肤透皮利切除术
Gregory W Hosier1, Darren T Beiko2, Heiko Yang3
1Department of Urological Sciences, University of British Columbia, Victoria, British Columbia, Canada.
European urology focus
|October 8, 2025
概括
门诊性皮肤瘤切除术 (PCNL) 与住院PCNL一样安全和有效,具有类似的并发症率和无结石的成功率. 这种方法支持更快的恢复,并可能降低结石治疗的成本.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 最少侵入性的手术
- 腎石病的管理方法
背景情况:
- 透皮石切除术 (PCNL) 是石去除的一个关键手术.
- 与住院PCNL相比,已提出门诊PCNL以改善患者康复并降低医疗保健成本.
研究的目的:
- 进行一项高质量的随机对照试验,比较门诊与住院PCNL.
- 评估门诊PCNL在并发症率方面的非劣势.
主要方法:
- 进行了一项多中心的非劣势性随机对照试验.
- 患者被随机分类并根据ASA状态,BMI,石头大小和研究地点进行分层.
- 主要结局是手术后4周内的并发症率.
主要成果:
- 门诊PCNL的并发症率为6%,住院PCNL为14% (p=0.4).
- 无石头的比率为77%的门诊和71%的住院PCNL (p=0.6).
- 两组之间没有观察到并发症率,再入院或无石头状态的显著差异.
结论:
- 门诊PCNL在并发症,无石头率和再入院方面表现出与住院PCNL相比的非劣势.
- 这些发现支持在经验丰富的中心使用门诊PCNL.
- 门诊PCNL为结石治疗提供了一个可行的替代方案,有可能提高患者的康复和成本效益.
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