2010年至2017年阿尔伯塔省社区抗生素处方模式的基于人口的研究:对抗生素管理的影响
Sofiya Manji1, Lynora Saxinger2, Lisa Cook3,4
1Research & Innovation, Public Health Evidence & Innovation, Alberta Health Services, Edmonton, AB, Canada.
概括
阿尔伯塔省的抗生素处方率整体保持稳定,但在皮肤感染和贫困地区增加. 特定的抗生素对急性囊炎和鼻炎等常见疾病显示出不同的趋势.
科学领域:
- 公共卫生 公共卫生
- 药学流行病学 药学流行病学
- 传染病流行病学 传染病流行病学
背景情况:
- 消费抗生素是抗菌素耐药性的关键因素.
- 了解社区的处方模式对于管理至关重要.
- 抗生素使用的时间趋势需要强大的量化方法.
研究的目的:
- 开发一种方法来量化社区抗生素消费.
- 确定阿尔伯塔省常见适应症抗生素处方的时间趋势.
- 根据年龄,性别,社会经济地位和症状分析处方模式.
主要方法:
- 一个算法将从业者索赔数据与药品发行 (2010-2017) 联系起来.
- 抗生素处方率以定义的每日剂量 (DDD) / 1000人/天来衡量.
- 肯德尔的Tau被用来分析时间趋势.
主要成果:
- 总体处方率稳定在10.09 DDD/1000人/天.
- 高龄女性和贫困地区的比例最高,贫困地区的增长趋势越来越大.
- 抗生素的处方增加了细胞炎和的条件; 尼特罗黄因的使用增加了急性囊炎.
结论:
- 急性囊炎,上呼吸道和皮肤感染是抗生素处方的主要驱动因素.
- 针对皮肤感染的抗生素处方日益增长的趋势凸显了针对性干预的必要性.
- 了解在多个层面处方抗生素的驱动因素可以提高社区抗生素管理.
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