牙周病与炎症标志物和妊娠糖尿病的关联:一个病例对照研究
Isa Temur1, Safak Necati Dönertas2, Aycan Dal Dönertaş3
1Department of Obstetrics and Gynecology, Faculty of Medicine, Niğde Ömer Halisdemir, University, Niğde, Türkiye.
BMC oral health
|October 8, 2025
概括
孕期糖尿病 (GDM) 的女性表现出较差的牙周健康状况和更高的DMFT分数. 怀孕期间体重增加是GDM最强的预测因素,表明代谢因素和口腔健康之间存在联系.
科学领域:
- 产科和妇科 产科和妇科
- 牙周病学 牙周病学
- 内分泌学 在内分泌学.
背景情况:
- 孕期糖尿病 (GDM) 是一种常见的妊娠并发症,与全身炎症和潜在的口腔健康问题有关.
- 关于在GDM怀孕中同时评估全身和口腔健康的研究有限.
- 这项研究调查了母亲口腔健康,炎症标志物和GDM之间的相互作用.
研究的目的:
- 检查妊娠糖尿病 (GDM) 和口腔健康参数之间的关系.
- 评估有或没有GDM的孕妇的血液炎症标志物.
- 为了确定孕妇GDM的预测因子.
主要方法:
- 一项病例对照研究,涉及40名患有GDM的孕妇和40名健康对照.
- 口腔健康通过斑块指数 (PI),牙指数 (GI),探测深度 (PD),临床附着水平 (CAL) 和DMFT指数进行评估.
- 统计分析包括曼 - 惠特尼U,奇平方和后勤回归;p <0.05是显著的.
主要成果:
- 治疗GDM组的PI,GI,PD和DMFT分数显著更高,表明口腔健康状况较差.
- 与对照组相比,GDM组的乙氨基酸水平明显较低 (p=0.011).
- 怀孕期间体重增加成为GDM的唯一显著预测因素 (p <0.05,OR = 1.117).
结论:
- 患有GDM的孕妇的牙周健康状况明显恶化,这表明GDM和牙周炎症之间存在联系.
- 怀孕期间的体重增加被认为是GDM的关键预测因素,强调了代谢因素的作用.
- 研究结果强调了监测GDM怀孕的口腔健康和管理体重增加的重要性.
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