时间蛋白质模式与糖尿病和血糖指标的关联
Hesti Retno Budi Arini1, Rebecca M Leech2, Sze-Yen Tan2
1Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, 3220, Australia. a.arini@deakin.edu.au.
Nutrition journal
|October 8, 2025
概括
每天摄入蛋白质的时间对美国成年人糖尿病风险或血糖控制没有显著影响. 这项研究发现,时间蛋白质模式与糖尿病,BMI或血糖水平之间没有关联.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 了解饮食模式在代谢健康中的作用至关重要.
- 时间性蛋白质摄入量,或当蛋白质在一天中被消耗时,是营养研究的一个新兴领域.
- 以前的研究还没有广泛探讨蛋白质摄入时间和糖尿病或相关代谢标志物之间的联系.
研究的目的:
- 为了研究美国成年人的时间蛋白质模式.
- 检查这些模式与糖尿病,体重指数 (BMI) 和血糖指标之间的关联.
- 根据其蛋白质消耗时间来识别不同的个人群体.
主要方法:
- 利用了国家健康和营养检查调查 (2017-2020) 的数据.
- 采用隐性可变混合物模型来识别三个不同的时间蛋白质摄入模式.
- 使用回归模型分析了与糖尿病患病率,BMI和血糖标记 (禁食葡萄糖,HbA1c,胰岛素,HOMA-IR) 的关联,并调整了混因素.
主要成果:
- 确定了男性和女性三种时间性蛋白质摄入模式.
- 在已识别的时间性蛋白质模式和糖尿病患病率,BMI或血糖指标之间没有发现统计学意义上的关联.
- 观察到一种模式与较低的血糖控制概率之间的潜在,但减弱的关联,受BMI的影响.
结论:
- 在这个成年人群中,暂时蛋白质摄入模式没有发现与糖尿病或血糖指标有关.
- 需要进一步的前性研究来探索蛋白质定时对糖尿病的影响.
- 未来的研究应该考虑不同蛋白质来源对这些关联的影响.
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