探索十种未充分利用的斯里兰卡水果的抗氧化特性和抗糖尿病潜力
P G N H Dharmasiri1,2, P Ranasinghe3, R G P T Jayasooriya4
1Faculty of Graduate Studies, General Sir John Kotelawala Defence University, Ratmalana, 10390, Sri Lanka.
BMC complementary medicine and therapies
|October 8, 2025
概括
来自Garcinia xanthochymus,Careya arborea和Syzygium zeylanicum的水果提取物具有强大的抗氧化和抗糖尿病特性. 这些天然产品为治疗糖尿病提供了有前途的治疗潜力.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 自然产品 化学 化学
背景情况:
- 糖尿病管理仍然是一个重大的全球健康挑战.
- 探索新型治疗剂的天然产品对于糖尿病治疗至关重要.
- 这项研究研究了各种水果植物提取物的植物化学物质,抗氧化剂和抗糖尿病特性.
研究的目的:
- 评估来自选定的水果植物的不同溶剂提取物的植物化学成分,抗氧化能力和体外抗糖尿病活性.
- 为了确定特定的水果提取物具有糖尿病管理的重大潜力.
主要方法:
- 总含量 (TPC) 和总黄含量 (TFC) 的量化.
- 使用铁还原功率 (FRAP),氧基吸收能力 (ORAC),DPPH和ABTS测试来评估抗氧化活性.
- 通过体外抗氨酶,抗葡萄糖酶和抗糖化试验来评估抗糖尿病潜力.
主要成果:
- 加尔西尼亚 (Garcinia xanthochymus) 的 (HX) 和乙烯酸 (EA) 分数分别显示出高TPC和TFC.
- 各种提取物显示出显著的抗氧化活性 (FRAP,ORAC,DPPH,ABTS).
- G. xanthochymus,Careya arborea的EA分数和Syzygium zeylanicum的HX分数表现出显著的抗氨酶和抗糖化活性,而Elaeocarpus angustifolia和其他EA分数显示出强烈的抗葡萄糖酶抑制.
结论:
- 乙酸 (EA) 分数的G. xanthochymus和C. arborea,和 (HX) 分数的S. zeylanicum,具有显著的体外抗氧化和抗糖尿病特性.
- 这些特定的水果提取物显示出作为糖尿病治疗候选者的潜力.
- 建议进行进一步的体内研究,以确认疗效并了解临床应用的作用机制.
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