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Updated: Jan 15, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

Published on: May 10, 2018

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规范翻译因子eIF1A和eIF5B调节重复关联非AUG翻译的启动步骤

Hayato Ito1, Kodai Machida2, Yuzo Fujino3

  • 1School of Life Science and Technology, Institute of Science Tokyo, S2-19, Nagatsuta 4259, Midori-ku, Yokohama 226-8501, Japan.

Nucleic acids research
|October 9, 2025
PubMed
概括

在C9orf72中重复扩张会导致神经退行. 研究人员发现,转化启动因子-真核体启动因子1A (eIF1A) 和真核体启动因子5B (eIF5B) 抑制了这种非正规的重复关联非AUG (RAN) 转化.

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