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Updated: Jan 15, 2026

Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice
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血小板驱动的单细胞激活通过HIF-1α-NLRP3-EGR-1轴促进缺氧性血栓炎症

Shankar Chanchal1, Kashika Singh1, Raishal Safdar1

  • 1Department of Biotechnology, Faculty of Life Sciences, Jamia Millia Islamia, New Delhi.

Haematologica
|October 9, 2025
PubMed
概括

缺氧通过激活HIF-1α-NLRP3炎症酶途径促进深静脉血栓 (DVT),导致无菌炎症和血栓形成. 针对这一轴为缺氧诱导的血栓炎症提供了潜在的治疗策略.

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