大鼻中阿斯伯吉洛症和动因菌病混合感染:一个病例报告
Reiji Kokubo1, Ryunosuke Umehara1, Yoshiaki Katada1
1Department of Radiology, Tokyo Medical University Ibaraki Medical Center, Ibaraki, JPN.
Cureus
|October 9, 2025
概括
本病例报告详细介绍了一种罕见的上鼻同时感染阿斯伯吉洛斯症和阿克丁诺米科斯症. 及时诊断和手术干预导致在这种独特的真菌和细菌鼻感染中取得了有利的临床进展.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 医学真菌学 医学真菌学
背景情况:
- 与Aspergillus和Actinomyces同时发生的鼻感染非常罕见.
- 患有类风湿性关节炎和糖尿病等潜在疾病的患者可能面临更高的风险.
- 性鼻水可能是复杂的鼻病理的症状.
研究的目的:
- 报告一个罕见的同时发生的阿斯珀吉洛斯症和大鼻中行为菌病的病例.
- 突出诊断挑战和成功管理这种双重感染.
- 审查有关混合真菌和细菌鼻感染的现有文献.
主要方法:
- 74岁的女性的临床表现,左侧有性鼻水.
- 诊断成像包括计算机断层扫描 (CT) 和磁共振成像 (MRI) 的鼻.
- 第三种类型的内镜外科手术,其遗传病理学证实了Aspergillus和Actinomyces.
主要成果:
- CT和MRI显示了多个鼻中的真菌球,表明真菌感染.
- 术后发现包括细菌质样物质,表明无氧感染.
- 组织病理学证实了Aspergillus hyphae和actinomycete群体,确定了混合感染的诊断.
- 在actinomycete群体中发现了Splendore-Hoeppli现象.
结论:
- 上鼻的混合阿斯伯吉洛症和上鼻的行为菌症是一种极其罕见的临床实体.
- 多模式诊断方法对于识别并存感染至关重要.
- 成功的治疗包括内镜外科手术,随后是抗生素治疗 (青素和阿莫西西林).
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