卡利指数与结石之间的关联:来自NHANES 2007-2010年的见解
Liangliang Dai1,2, Chenjie Qiu3
1Department of Urology, Wujin Hospital Affiliated With Jiangsu University, Changzhou 213004, China.
Mediators of inflammation
|October 9, 2025
概括
在C-反应蛋白 (CRP) - 专 - 淋巴细胞 (CALLY) 指数显示显著的反向关联与结石风险. 较高的CALLY指数得分与患结石的可能性降低相关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 生物标志物 生物标志物
- 炎症 炎症是一种炎症.
背景情况:
- 结石是一个日益严重的健康问题,其发病率与炎症,饮食和免疫状况有关.
- 综合标记物C反应性蛋白 (CRP) - 专 - 淋巴细胞 (CALLY) 指数在癌症中显示出预后效用,但其在结石形成中的作用尚未检查.
- 这项研究调查了CALLY指数与结石风险的关联.
研究的目的:
- 探索CALLY指数与结石形成风险之间的关系.
- 分析2007-2010年国家健康和营养检查调查 (NHANES) 的数据.
主要方法:
- 利用了来自10562名NHANES参与者的数据 (2007-2010年).
- 通过自我报告问卷评估石状况.
- 采用多变量逻辑回归,受限立方线 (RCS) 模型和子组分析来评估CALLY指数关联.
主要成果:
- 患有结石的个体的CALLY指数平均值较低.
- 在CALLY指数和结石风险之间发现了显著的反向关联.
- 与最低四分位数相比,CALLY指数的最高四分位数与结石风险降低了27.3%,证实了非线性关系.
结论:
- 卡利指数显示,与结石风险有负面关联.
- 这表明CALLY指数可能作为结石发展的潜在指标.
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