相关概念视频
01:31Proofreading
8.7K
Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...
Errors During Replication are Corrected by the DNA Polymerase...
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01:43Proofreading
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Overview
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01:16Clot Retraction and Fibrinolysis
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After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
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01:36Mismatch Repair
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Overview
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01:20Mismatch Repair
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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
6.3K
01:02Long-patch Base Excision Repair
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Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
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概括
这项研究纠正了先前发表的一篇文章的DOI. 校正确保了适当的引用和对研究结果的访问,以便在未来进行科学调查.
科学领域:
- 医学研究 医学研究
- 科学出版科学出版
背景情况:
- 确保科学出版物的准确性对于研究的完整性至关重要.
- 适当的引用有助于追踪和验证科学信息.
研究的目的:
- 纠正以前发表的文章的数字物体标识符 (DOI).
- 确保研究的准确引用和可访问性.
主要方法:
- 发布了一份纠正通知.
- 在TurkPediatriArs.发表的文章中提供了正确的DOI.
主要成果:
- 文章DOI已经被纠正.
- 正确的DOI现在可供引用.
结论:
- 准确的DOI对于科学文献至关重要.
- 这种纠正提高了研究的可发现性和引用准确性.
