伟大的模仿者:肺腺癌与间歇性肺部疾病 - - 像演示
Mahima Upadhyay1, Prajwal Shanker2, Susheel Joshi3
1Department of Internal Medicine, Hurley Medical Center, Michigan State University, Flint, USA.
European journal of case reports in internal medicine
|October 9, 2025
概括
侵入性粘膜腺癌 (IMA) 可以模仿诸如间歇性肺病之类的肺部疾病,延迟诊断. 及时的组织活检对于准确诊断和及时治疗这种罕见的肺癌亚型至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 一名52岁的女性吸烟史和新诊断的慢性阻塞性肺病 (COPD) 呈现出呼吸困难.
- 在COPD恶化后的非典型成像发现促使了自身免疫评估,该评估是负面的.
研究的目的:
- 突出突发性粘膜腺癌 (IMA) 所带来的诊断挑战.
- 强调在有呼吸道症状恶化和吸烟史的患者中考虑IMA的重要性.
主要方法:
- 一个患有呼吸短促和血栓塞的病人的病例介绍.
- 诊断工作包括成像,自身免疫评估和带有活检的支气管镜检查.
- 组织病理学检查显示侵入性粘膜腺癌.
主要成果:
- 尽管最初的表现模仿了间歇性肺病,但被诊断出侵袭性粘膜腺癌.
- 支气管膜洗细胞学产生了假阴性结果.
- 通过活检迅速取取组织样本证实了诊断.
结论:
- 侵入性粘膜腺癌可以异常呈现,模仿良性肺部疾病,导致诊断延迟.
- 像地面玻璃不透明等成像发现可能表明间歇性肺部疾病,导致不必要的调查.
- 通过活检进行组织病理学确认是必不可少的,因为在IMA中,支气管支气管支气管洗细胞学可能会产生假阴性.
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