化表皮质质瘤的恶性转变:系统性审查
Elton Fernandes Barros1, Esllen Carla Ferreira de Araújo Vasconcelos2, Ellen da Silva Gonçalves3
1Department of Dentistry, State University of Paraíba- UEPB, Campina Grande, PB, Brazil.
Journal of clinical and experimental dentistry
|October 9, 2025
概括
化表皮质口腔瘤 (CEOT) 的恶性转变很少见,但可能发生. 这次审查确定了这些积极的CEOT病例的关键临床病理特征,治疗策略和结果.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 新生体 新生体.
背景情况:
- 结石化表皮性质性瘤 (CEOT) 是一种罕见的良性质性瘤.
- 对CEOT恶性转变的了解很少.
- 这项研究系统地审查了恶性转变的CEOT病例.
研究的目的:
- 为了确定恶性转变的CEOT的临床病理概况.
- 为了确定这种罕见的瘤的诊断辅助工具.
- 为适当的治疗方法综合信息.
主要方法:
- 按照PRISMA指南进行系统审查.
- 搜索了多个数据库,查找经过基因病理学确认的CEOT恶性转变病例.
- 进行了定性描述性和偏见风险分析.
主要成果:
- 审查了9例病例,平均年龄为59.44岁,主要是男性,影响下.
- 常见的发现包括明确的细胞变异,高线粒活性,细胞异型和高Ki-67表达.
- 手术是主要治疗方法;复发发生在33.3%的转变病例中,结果为77.8%.
结论:
- 本综述建立了恶性CEOT的临床病理学概况.
- 识别的特征可以帮助诊断和治疗规划.
- 了解这些特征对于管理这种罕见的实体至关重要.
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