相关实验视频

Updated: Jan 15, 2026

In Vitro Three-Dimensional Sprouting Assay of Angiogenesis Using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing
08:04

In Vitro Three-Dimensional Sprouting Assay of Angiogenesis Using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing

Published on: May 11, 2021

3.3K

缺少ATF3促进了美皮间的结合,并增强了胚胎干细胞内皮分化

Zongyue Jiang1, Lide Su1,2, Cuiting Chen3,4

  • 1Department of Cardiovascular Surgery, Xiang'an Hospital of Xiamen University (Z.J., L.S., R.H., M.W., A.G., J.L., Z.L.), Xiamen University, Fujian, China.

Arteriosclerosis, thrombosis, and vascular biology
|October 9, 2025
PubMed
概括

在胚胎干细胞中淘汰Atf3 (激活转录因子3),促进它们分化为内皮细胞 (ECs). 这一过程涉及中皮层线条的结合和Rap1信号通路的激活,从而增强EC功能.

关键词:
激活转录因子3的激活因子胚胎干细胞是一种胚胎干细胞.它们是内皮细胞的内皮细胞.这里是 mesoderm 和 mesoderm 的区别.

更多相关视频

TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing07:05

TGF-β-mediated Endothelial to Mesenchymal Transition EndMT and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing

Published on: February 26, 2021

5.7K
Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

11.7K

相关概念视频

Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
3.3K