骨髓病变和2型糖尿病
Lucian Batista de Oliveira1,2, Vanessa de Oliveira E Silva3, Ítalo Caio Lopes Jucá3
1Division of Endocrinology and Diabetes, Agamenon Magalhães Hospital, Faculty of Medical Sciences, University of Pernambuco (UPE), Recife, Brazil. lucian.batista@upe.br.
概括
骨髓炎,或脂肪透到骨肌肉中,与2型糖尿病 (T2DM) 有关. 本综述强调了骨髓炎与增加T2DM风险之间的关联,强调了公共卫生影响.
科学领域:
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
- 医疗成像医学成像
背景情况:
- 骨髓炎涉及骨肌肉中的脂肪积累,通常与衰老和肥胖有关.
- 这种情况与胰岛素抵抗 (IR),高胰岛素血症以及2型糖尿病 (T2DM) 和心血管疾病的风险增加有关.
研究的目的:
- 审查现有证据,将骨髓炎与T2DM联系起来.
- 编制流行病学数据并确定有关骨髓炎和T2DM的文献差距.
主要方法:
- 全球十项观察性研究的系统综述.
- 分析数据,将肌肉骨瘤测量 (CT,MRI) 与T2DM发病率和相关代谢标志物联系起来.
主要成果:
- 在肌肉骨病和较高的T2DM发病率之间发现了一致的关系.
- 骨髓炎与胰岛素抵抗,血糖控制较差,炎症标志物升高和冠状动脉疾病风险相关.
结论:
- 骨髓炎和T2DM有着重要的关系,具有重大的公共卫生影响.
- 肌肉骨病评估的标准化和进一步的干预研究对于治疗策略至关重要.
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