上升的感染是产前出血的主要原因:一个病例对照研究
Iván Rabinovich Orlandi1,2, Guido Patricio Gromadzyn3, Marta C Cohen1,4,5
1Sheffield Children NSH FT, Sheffield, UK.
Acta obstetricia et gynecologica Scandinavica
|October 9, 2025
概括
胎盘断裂和上升感染是产前出血的关键原因. 组织病理学改善了诊断,有助于了解未来怀孕中复发风险.
科学领域:
- 产科 产科 产科 产科 产科
- 病理学 病理学 病理学
- 围产儿医学 围产儿医学
背景情况:
- 胎盘断裂,即胎盘过早分离,影响2-3%的怀孕.
- 断裂的临床诊断具有挑战性,与病理发现的相关性很低 (灵敏度为30.2%).
- 准确的诊断对于管理结果和了解复发风险至关重要.
研究的目的:
- 为了确定与产前出血相关的胎盘疾病.
- 评估临床诊断和断裂的组织病理学发现之间的相关性.
主要方法:
- 对285份胎盘组织病理学报告进行了回顾性分析.
- 与对照组 (n=104) 相比,发生产前出血/脱胎的病例 (n=181) 的比较.
主要成果:
- 附着的血块,带超卷,以及上升的感染/chorioamnionitis是产前出血的重要发现.
- 组织学断裂和膜炎独立地与产前出血有关.
- 与对照组 (39周) 相比,在产前出血组观察到更低的妊娠年龄 (33周).
结论:
- 上升性感染和组织学断裂是产前出血中常见的胎盘状况,表明多因素病因.
- 这些发现对于评估临床影响,患者的治疗结果和复发风险至关重要.
相关概念视频
Sexually Transmitted Infections
921
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
921
Acute Pyelonephritis I: Introduction
482
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
482
Endocarditis I: Introduction
392
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
392
Healthcare Associated Infections II: Preventive Measures
3.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.6K
Urinary Tract Infection II: Pathophysiology
567
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
567
Factors Affecting the Risk of Infection
13.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.2K


