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人类的性多态性和预测范围的形态变异在人类骨的性别指标
1Anthropology Department, CUNY Graduate Center, New York, New York, USA.
American journal of biological anthropology
|October 9, 2025
概括
骨性别指标表达在不同的跨性别变异中有所不同. 这项研究预测了特定的跨性别特征的低,中或高表达,有助于未来对人类骨变异的研究.
科学领域:
- 法医人类学 法医人类学.
- 内分泌学 在内分泌学.
- 人类的变化人类的变化
背景情况:
- 人类的性别通常被视为二形,但存在显著的差异.
- 双性人拥有男性,女性和/或非典型特征的组合.
- 跨性别个体中性别特征的骨变异在很大程度上仍然没有特征.
研究的目的:
- 预测各种跨性别变异中的骨性别指标的表达水平.
- 为了解跨性别个体的骨变异提供一个框架.
主要方法:
- 预测是由关于性别间变化的内分泌学数据提供信息.
- 骨性别指标表达被分类为低,中等或高的九种跨性别形式.
主要成果:
- 低表达预测完全的雄激素不敏感性 (CAIS),单体X和XY淋巴腺失调.
- 预测的5α-减少酶 (5α-RD),局部雌激素不敏感性 (PAIS),先天性上腺增生 (CAH) (21-基酶),Müllerian生成和XXY的中间表达.
- 预测CAH (11β-基酶) 和hypospadias的高表达.
结论:
- 这些预测为测试关于跨性别骨变异的假设提供了基础.
- 研究需要可访问的骨遗骸和/或数据与跨性别个体的同意.
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