在急性链球菌后淋巴结膜炎中发烧:患病率和临床意义
Shiri Curelaru1, Elina Gelman1, Asaf Lebel1
1Pediatrics Department B, HaEmek Medical Center, Yitzhak Rabin Boulevard 21, Afula, Israel.
概括
发烧常见于儿科急性链球菌后血球膜炎 (APSGN),并与更长的住院时间有关. 然而,发烧对这些儿童的短期或中期结局没有影响.
科学领域:
- 儿科脏病学 儿科脏病学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 急性链球菌后球腺炎 (APSGN) 是A组链球菌 (GAS) 感染后的一种常见的儿科病.
- 在APSGN中很少报告发烧,其临床意义尚不清楚.
- 了解发烧的作用对于评估儿科APSGN的脏结果至关重要.
研究的目的:
- 为了确定儿科APSGN患者发烧的流行率.
- 评估发烧对APSGN.结局的临床意义.
- 评估儿童发烧,炎症标志物和GAS感染之间的关联.
主要方法:
- 儿科APSGN患者 (2005-2024) 的回顾性分析.
- 纳入标准:临床表现为血球膜炎,低C3和GAS感染证据.
- 在发烧和无发烧组之间比较短期和中期结局 (eGFR,血压,尿液分析).
主要成果:
- 在69名儿科APSGN患者中的34.8%出现了发烧.
- 发烧患者的C-反应蛋白水平较高,住院时间较长.
- 两组之间没有观察到丸炎严重程度或中期结局的显著差异.
结论:
- 发烧是儿科APSGN的常见症状,通常与病毒感染有关.
- 虽然发烧与炎症增加和住院时间增加有关,但它不会预测短期或中期病预后会更差.
- 发烧不应被认为是儿科APSGN.的坏结局的指标.
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