对不同植入物表面脱污技术对细菌负载和表面完整性的评估:一个体外研究
Ece Açıkgöz-Alparslan1, Ayşegül Kurt2, Ufuk Bağcı3
1Department of Periodontology, Faculty of Dentistry, Trakya University, Edirne, Türkiye. eceacikgoz@trakya.edu.tr.
Lasers in medical science
|October 9, 2025
概括
在2W的Erbium,Chromium:Yttrium-Scandium-Gallium-Garnet (Er,Cr:YSGG) 激光器有效地从圆盘中去除了金黄色葡萄球菌生物膜. 这种激光处理在减少细菌和保持表面完整性之间提供了最佳的平衡.
科学领域:
- 生物材料科学 生物材料科学
- 微生物学 微生物学
- 牙科材料 牙科材料
背景情况:
- 植入物容易受到黄金葡萄球菌生物膜污染.
- 有效的净化对植入物成功和寿命至关重要.
- 评估生物膜去除和表面保护的各种技术是必不可少的.
研究的目的:
- 为了评估不同污染方法的有效性,在带有 Staphylococcus aureus 生物膜的圆盘上.
- 评估这些方法对表面化学和地形学的影响.
- 确定最佳的技术,平衡细菌去除和表面完整性.
主要方法:
- 圆盘被 Staphylococcus aureus 生物膜污染了.
- 测试了五种净化方案:克瑞特 (TC),两个Er,Cr:YSGG激光设置 (LI1,LI2),用甘氨酸粉末 (AGP) 进行空气磨损,以及用赫西丁 (AEP) 进行红粉末.
- 使用CFU计数,CLSM和SEM量化细菌减少;表面分析涉及SEM,XPS和形状测量.
主要成果:
- 所有方法都显著降低了细菌数量 (p < 0.05),Er,Cr:YSGG激光在2W (LI2) 时显示出最大的日志减少.
- LI2,TC和AEP显示了可行的生物质减少 (p<0.05),而AGP的效果最差.
- LI2和AEP极少改变了表面化学,增加了氧含量,而TC导致了痕和增加了粗度,AGP/AEP留下了残留物.
结论:
- 没有一种单一的方法可以完全根除金黄色葡萄球菌生物膜.
- 2W的Er,Cr:YSGG激光器提供了最有利的结果,有效地减少了细菌,同时保持了表面的特性.
- 优化的激光参数和赫西丁丰富的粉末是有希望的,安全的净化选择.
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