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Updated: Jan 15, 2026

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由JAK3/STAT1通路调节的AIM2促进了由同时辐射和PD-1阻塞引起的肠壁功能障碍中的PANoptosis

Jingru Chen1, Yuxuan Tao1, Qingxin Wang2

  • 1Department of Radiation Oncology, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin, China.

Apoptosis : an international journal on programmed cell death
|October 9, 2025
PubMed
概括

放射治疗和免疫治疗通过AIM2-介导的PANoptosis引起肠道损伤. 抑制JAK3或TMAO可能会降低这种毒性.

关键词:
胆的代谢 胆的代谢免疫疗法是一种免疫疗法.肠道损伤 肠道损伤 肠道损伤辐射辐射是一种辐射.这就是TMAOO.

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