经更年期前的认知功能:一个更新的系统审查和元分析
Amanda Bangle1, Danielle Williams1, Jared Walters2
1School of Applied Psychology, Griffith University.
Psychology and aging
|October 9, 2025
概括
在绝经前期,与绝经前妇女相比,女性会经历认知变化,特别是使用标准化分期时. 绝经前期和绝经后期妇女之间的认知功能差异取决于所使用的研究方法.
科学领域:
- 生殖衰老和认知健康
背景情况:
- 绝经前期涉及激素波动影响认知,导致经常的主观投诉,如忘记.
- 现有研究表明,经更年期期间的认知变化由于不同的方法和比较小组而存在不一致.
- 报告了客观认知缺陷,但研究结果在注意力,记忆力和执行功能方面存在差异.
研究的目的:
- 系统地审查和分析与绝经前和绝经后妇女相比,绝经前妇女的认知差异.
- 通过检查方法变化的影响来澄清不一致的发现,包括生殖分期标准.
- 为了更好地了解更年期过渡期间的认知变化,以改善临床评估和干预措施.
主要方法:
- 对26项涉及9428名参与者的研究进行了系统审查和元分析.
- 在绝经前和绝经前妇女之间比较认知结果 (21项研究).
- 在绝经前期和绝经后妇女之间比较认知结果 (21项研究),分析调节者,如生殖衰老工作室的阶段 (STRAW+10) 标准.
主要成果:
- 绝经前妇女比绝经前妇女表现较差的认知结果 (中等效果),特别是在使用STRAW+10标准的研究中.
- 在绝经前期和绝经后妇女之间没有发现任何显著的认知差异.
- 没有使用STRAW+10标准的研究表明,绝经前期女性的认知能力比绝经后期更好;绝经前期女性的客观认知功能更好,但与绝经后女性相比,自我报告结果更差.
结论:
- 标准化生殖分期 (STRAW+10) 对于准确评估绝经前期的认知变化至关重要.
- 整合主观和客观认知评估对于全面的研究至关重要.
- 了解更年期前的认知变化可以增强中年妇女认知健康的临床支持和干预措施.
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